论文部分内容阅读
目的:探讨泌尿系结石患者与健康体检者结石相关因素。方法:对300例泌尿系结石患者的结石成分进行分析,并结合血生化及24 h尿液分析结果,与300例健康体检者进行对照研究。结果:尿石症患者中,草酸钙结石232例(77.3%),磷酸盐结石50例(16.7%),感染性结石9例(3%),尿酸结石9例(3%)。结石患者血清镁、钙、磷及24 h尿氯、钙、镁、磷、尿酸显著高于健康体检者(P<0.05),而血钾、尿枸橼酸则显著低于健康体检者(P<0.05)。结论:尿结石与多种代谢异常关系密切,结石成分及代谢评估对泌尿系结石的成因、治疗和预防有重要临床指导意义。
Objective: To investigate the related factors of stones in urolithiasis and healthy subjects. Methods: The stones of 300 patients with urolithiasis were analyzed, and the results of blood biochemistry and 24 h urine analysis were compared with those of 300 healthy subjects. Results: Among the patients with urolithiasis, 232 cases (77.3%) of calcium oxalate stones, 50 cases (16.7%) of phosphate stones, 9 cases (3%) of infectious stones and 9 cases (3%) of uric acid stones. Calcium, phosphorus and 24-hour urinary chlorine, calcium, magnesium, phosphorus and uric acid in patients with stone were significantly higher than those in healthy people (P <0.05), while serum potassium and urine citric acid were significantly lower than those in healthy people <0.05). Conclusion: Urinary calculus is closely related to various metabolic abnormalities. It is of great clinical significance to evaluate the causes, treatment and prevention of urolithiasis by evaluating the composition and metabolism of calculus.