论文部分内容阅读
目的观察倍他乐克对慢性收缩性中、重度心力衰竭即NYHA(纽约心脏病协会)心功能分级Ⅲ、Ⅳ级的疗效。方法回顾总结我院2002年8月至2008年8月收治的48例慢性收缩性心力衰竭,NYHA心功能分级Ⅲ、Ⅳ级患者,按治疗方法不同分两组:对照组25例,常规利尿、血管紧张素转换酶抑制剂(ACEI)、强心、醛固酮受体拮抗剂治疗;治疗组23例,常规治疗的同时加倍他乐克治疗12个月,观察两组临床疗效,近期及1年内死亡率,治疗前后超声指标的变化,再次住院情况。结果治疗组治疗后其临床疗效、近期及1年内死亡率、再次住院人数、超声指标均较对照组有明显改善(p<0.05)。结论慢性收缩性心力衰竭,NYHA心功能分级Ⅲ、Ⅳ级,在理想利尿效果作保驾护航的同时,应用倍他乐克能提高疗效,提高生存率,减少住院次数,改善心肌重构。
Objective To observe the efficacy of metoprolol in chronic constrictive and moderate heart failure (NYHA New York Heart Association) grade Ⅲ and Ⅳ. Methods A retrospective review of 48 patients with chronic systolic heart failure and NYHA cardiac function grade Ⅲ and Ⅳ admitted from August 2002 to August 2008 in our hospital was divided into two groups according to the different treatment methods: control group (n = 25), conventional diuretic, Angiotensin converting enzyme inhibitor (ACEI), cardiac, aldosterone receptor antagonist treatment; 23 cases of treatment group, conventional treatment at the same time double taurek treatment for 12 months, the two groups were observed clinical efficacy, the recent and 1 year of death Rate, changes in ultrasound before and after treatment, hospitalization again. Results After treatment, the clinical curative effect, the short-term and 1-year mortality, the number of hospitalizations again and the ultrasound indexes in the treatment group were significantly improved (p <0.05). Conclusions Chronic systolic heart failure, NYHA class Ⅲ and Ⅳ, can protect the ideal diuretic effect. At the same time, the application of metoprolol can improve the curative effect, increase the survival rate, reduce the frequency of hospitalization and improve myocardial remodeling.