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目的:了解广州地区产妇母乳铅含量与母血、脐血铅含量之间的相关性。方法:采用电感耦合等离子体质谱仪(ICP-MS)对广州地区500例产妇抽取母血、脐血、母乳中铅含量进行测定,并进行三者之间的相关性分析。结果:母血铅含量为0~67.590μg/L,均值为(22.005±12.861)μg/L,脐血铅含量为0~69.370μg/L,均值(26.760±9.223)μg/L,母乳铅含量为0~80.420μg/L,均值为(4.474±8.760)μg/L,母血铅与脐血铅含量呈显著正相关(r=0.341,P=0.001),母乳中铅含量与母血中铅含量的相关性没有统计学意义(r=0.064,P=0.367),母乳中铅含量与脐血中铅含量的相关性没有统计学意义(r=0.001,P=0.995)。结论:母血铅含量与脐血铅含量成正相关,血铅可通过胎盘转运给胎儿,母乳中铅含量较母血中铅含量低,母乳喂养是安全的。
Objective: To understand the correlation between maternal milk lead content and maternal blood and umbilical cord blood lead content in Guangzhou area. Methods: The lead contents in maternal blood, umbilical blood and breast milk of 500 maternal mothers in Guangzhou were determined by Inductively Coupled Plasma Mass Spectrometry (ICP-MS), and the correlation between them was analyzed. Results: The lead levels in maternal blood ranged from 0 to 67.590μg / L with mean values of (22.005 ± 12.861) μg / L, lead levels in cord blood ranged from 0 to 69.370 μg / L, with mean values of 26.760 ± 9.223 μg / L, (4.474 ± 8.760) μg / L, and there was a significant positive correlation between lead and umbilical cord blood lead (r = 0.341, P = 0.001). The correlation between lead in breast milk and lead (R = 0.064, P = 0.367). The correlation between lead in breast milk and lead in cord blood was not statistically significant (r = 0.001, P = 0.995). Conclusion: The lead content in maternal blood is positively correlated with the lead content in umbilical cord blood. Blood lead can be transported to the fetus through the placenta. The lead content in breast milk is lower than that in maternal blood and breastfeeding is safe.