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目的分析急性出血性结膜炎暴发特点,探讨暴发原因,评价干预效果。方法对报告病例数据进行统计分析,对发病因素开展横断面调查,并对暴发进行控制干预。结果2007年7月20日至11月26日,深圳市某企业共报告和隔离11 118例急性出血性眼结膜炎病例,其罹患率为2957.80/10万,显著高于2006年的433.72/10万,P<0.0001。其发病高峰在8月14日至9月4日;观澜园区职工的罹患率为5146.32/10万,明显高于龙华园区职工的2080.38/10万,P<0.0001。不同工作部门和宿舍区职工罹患率有明显的差异。行政干预措施前对病例调查发现,有37.47%的病例在发病后≥2 d未能发现和隔离;病例所在办公室和寝室开展疫点终末消毒分别为38.43%和43.22%;仅有26.42%知道本病还可通过空气传播。行政干预措施后该企业病例搜索和隔离、终末消毒,对职工开展宣传教育等各项技术性控制措施完全落实,暴发终止。结论该企业2007年急性出血性结膜炎暴发呈夏季发病高峰,其暴发强度大于2006年;病例发现和隔离不及时是传染源在人群中快速扩散形成暴发的重要因素;行政干预措施是保障企业自建隔离区、早期发现和隔离患者等各项技术性干预措施能完全实施,暴发得以快速控制的关键。
Objective To analyze the characteristics of acute hemorrhagic conjunctivitis outbreaks, discuss the causes of outbreak and evaluate the effect of interventions. Methods Statistical analysis of the reported case data, cross-sectional investigation of the incidence of factors, and control of the outbreak of intervention. Results From July 20, 2007 to November 26, 2007, a total of 11 118 cases of acute hemorrhagic conjunctivitis were reported and isolated by a Shenzhen company. The attack rate was 2957.80 / 100,000, which was significantly higher than that of 433.72 / 10 in 2006 Million, P <0.0001. The peak incidence peaked from August 14 to September 4; the attack rate of staff in Mission Park was 5146.32 / 100000, which was significantly higher than that of Longhua Park staff of 2080.38 / 100000, P <0.0001. There were significant differences in the attack rates among staff in different work departments and dormitory areas. Before the administrative intervention, we found that 37.47% cases failed to find and isolate more than 2 days after the onset of illness. The terminal disinfection of the office and dormitory were 38.43% and 43.22%, respectively; only 26.42% knew The disease can also be spread through the air. After the administrative interventions, the technical control measures such as search and quarantine of the case of the enterprise, terminal sterilization, propaganda and education for employees were fully implemented and the outbreak was terminated. Conclusions The outbreak of acute hemorrhagic conjunctivitis in 2007 showed peak incidence in summer and its outbreak intensity was greater than that in 2006. The detection and isolation of cases were not timely as an important factor in the rapid spread of infectious agents in the population and the administrative intervention was to protect enterprises from The key to rapid control of outbreaks is the full implementation of technical interventions such as isolation, early detection and isolation of patients.