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糖尿病肾病(diabetic nephropathy,DN)是糖尿病重要微血管并发症之一,糖尿病肾病导致慢性肾脏病(chronic kidney disease,CKD)也越来越受到重视,在西方国家糖尿病肾病已成为导致终末期肾病的首位病因[1]。既往研究[2-4]均已证实,高血压既是糖尿病肾病的主要特征,也是其重要的危险因素之一。收缩性高血压和舒张性高血压均可促进糖尿病肾病的发展,加速肾功能减退恶化;而糖尿病肾病亦可进一步导致血压的升高。
Diabetic nephropathy (DN) is one of the important microvascular complications of diabetes. Diabetic nephropathy leads to more and more attention of chronic kidney disease (CKD). In western countries, diabetic nephropathy has become the first cause of end-stage renal disease Etiology [1]. Previous studies [2-4] have confirmed that hypertension is not only the main feature of diabetic nephropathy, but also one of the important risk factors. Systolic hypertension and diastolic hypertension can promote the development of diabetic nephropathy, accelerated deterioration of renal dysfunction; and diabetic nephropathy can also lead to increased blood pressure.