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目的 探讨对顽固性颞叶癫痫的术前定位方法.方法 将 M R 对海马硬化的诊断作为一重要参考指标与 E E G 检查相结合,对12 例顽固性颞叶癫痫进行术前定位诊断,并与术中皮层 E E G 检查结果和术后随访结果比较.结果 M R 检查发现9 例海马硬化,皮层 E E G 证实有同侧颞叶内侧放电,行选择性海马杏仁核切除术后病理证实海马硬化;未发现海马硬化改变3 例行前颞叶切除术.随访0?5 ~2 年,疗效满意.结论 E E G 是诊断颞叶癫痫的最重要手段, M R 发现海马硬化对致痫灶定位有重要意义.“,”Objective To discuss the way for localizing the epilepsy foci in intractable temporal epilepsy preoperatively. Methods We combined“hippocampal sclerosis” (HS) diagnosed by MR with the result of EEG to localize the epileptic foci in temporal epilepsy in 12 patients, and compared them to the result of cortex EEG and follow up. Results 9 patients who were thought to have HS accepted selective amygdalo hippocampectomy, intra operative EEG showed epileptic electrical activity in the medial temporal region, post operative pathological examination proved HS. Another 3 patients who were not found to have HS underwent temporal lobectomy. A follow up study from 6 months to 2 years was performed in all patients. The result was satisfactory. Conclusions EEG is the most important way to localize epileptic foci in temporal lobe epilepsy, MR can be a great help when HS is found.