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英《柳叶刀》第2卷第8252期(1981年)社论:正常人的胃液通常是无菌的,或每毫升含有少于10~5的细菌。这些细菌大多数来自口腔或食物。维持胃内的环境曾一度被认为要取决于胃液中的几种成分。而在体外,微生物被迅速致死,好象主要是盐酸的pH作用。当盐酸分泌减少或缺乏时,细菌的数量增加,常超过每毫升10~6,而且细菌的种类也增多,包括粪便细菌如大肠杆菌、粪链球菌和细菌样微生物。上述改变在恶性贫血和胃癌以及胃切除术后的病人中颇为多见。这时胃内菌丛的改变也许受到
Volume 2, No. 8252 (1981) Editorial: Normal human gastric juice is usually sterile or contains less than 10 to 5 bacteria per ml. Most of these bacteria come from the mouth or food. It was once thought to depend on several components of the gastric juice to maintain the environment in the stomach. In vitro, microbes are rapidly lethal, as if they are mainly the pH of hydrochloric acid. When the secretion of hydrochloric acid is reduced or absent, the number of bacteria increases, often over 10 to 6 per milliliter, and species of bacteria also increase, including fecal bacteria such as Escherichia coli, Streptococcus faecalis and bacterial-like microorganisms. The above changes are pervasive in patients with pernicious anemia and gastric cancer and after gastrectomy. At this time, changes in the stomach flora may be affected