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The Skyrme energy density functional is applied to study the ground state properties of a series of finite nuclei.The charge rms radii, neutron rms radii, and the neutron skin thickness for some nuclei are calculated and compared with the experimental data. The constraint on the effective interactions, especially, the density dependence of the isospin-dependent part of Skyrme interactions is extracted by the data of neutron skin thicknesses of 208 pb and isotopes of Sn.