论文部分内容阅读
目的评价新沂市40岁以下健康人群的风疹抗体水平。方法以新沂市2012年监测人群为基础,选取500名受试者,采集静脉血约2 m L,采用酶联免疫吸附试验检测血清中风疹抗体浓度,使用Stata 9.2软件分析人群总体抗体水平、评价人群免疫力和年龄、疫苗接种对抗体水平的影响。结果 500名监测对象中,风疹抗体阳性者382名,阳性率为76.4%,GMC为46.8 IU/m L。在1.5岁~,3岁~和5岁~组中,0针次和1针次风疹疫苗接种后抗体阳性率及GMC比较差异均无统计学意义(P>0.05)。接种1针次风疹疫苗者中,8月龄~,1.5岁~,3岁~和5岁~组抗体阳性率比较差异无统计学意义(χ2=0.3724,P=0.946),组间抗体GMC比较差异无统计学意义(F=1.91,P=0.130)。结论风疹具有较高的自然感染率,8月龄以下婴儿和20~40岁流动人口是新沂地区风疹控制的薄弱环节。
Objective To evaluate the level of rubella antibody in healthy people under the age of 40 in Xinyi City. Methods Based on the monitoring population of Xinyi City in 2012, 500 subjects were selected and the venous blood was collected for about 2 m L. Serum anti-rubella antibody concentration was detected by enzyme-linked immunosorbent assay (ELISA), and the overall antibody level was analyzed by Stata 9.2 software. Evaluation of population immunity and age, the impact of vaccination on antibody levels. Results Among the 500 subjects, 382 were positive for rubella antibodies, with a positive rate of 76.4% and a GMC of 46.8 IU / m L. In 1.5 years old, 3 years old and 5 years old group, there was no significant difference in antibody positive rate and GMC between 0 and 1 needles after rubella vaccination (P> 0.05). There was no significant difference in the positive rate of antibody between 8 months old, 1.5 years old, 3 years old and 5 years old group (χ2 = 0.3724, P = 0.946), and the antibody GMC among the groups The difference was not statistically significant (F = 1.91, P = 0.130). Conclusion Rubella has a high natural infection rate. Infants under 8 months of age and floating population aged 20 to 40 are the weakest link in the control of rubella in Xinyi District.