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目的探讨血脂正常的原发性高血压患者微量白蛋白尿与颈动脉粥样硬化(carotid atherosclerosis,CAS)的关系。方法血脂正常的原发性高血压患者169例,行颈动脉彩色多普勒超声检查,测量左、右颈动脉内膜-中层厚度,根据测量结果分为斑块组92例与无斑块组77例,将CAS分为0-4级并检测尿微量白蛋白水平。结果斑块组尿微量白蛋白水平高于无斑块组(P<0.01);CAS 0,1,2,3,4级尿微量白蛋白水平比较差异均有统计学意义(P<0.05)。结论血脂正常的原发性高血压患者微量白蛋白尿与CAS发生及程度呈正相关。
Objective To investigate the relationship between microalbuminuria and carotid atherosclerosis (CAS) in patients with essential hypertension with essential hypertension. Methods A total of 169 patients with essential hyperlipidemia and carotid artery color Doppler echocardiography were used to measure the intima - media thickness of the left and right carotid arteries. According to the measurement results, 92 patients were divided into plaque group and non - plaque group 77 cases, the CAS is divided into 0-4 level and urine microalbumin level. Results Urine microalbuminuria in plaque group was higher than that in non-plaque group (P <0.01). There was significant difference in urine microalbuminuria between CAS 0,1,2,3 and 4 levels (P <0.05). Conclusion Microalbuminuria in patients with normal serum lipids is positively correlated with the occurrence and extent of CAS.