脑活素与胞二磷胆碱在新生儿缺氧缺血性脑病中的疗效观察

• 作 者: 张淑霞 于岫岩 廉丽敏 韩婉茹 霍丽春 钱艳红
• 机 构: 黑龙江齐齐哈尔市第二医院儿科!161006,黑龙江齐齐哈尔市第二医院儿科!161006,黑龙江齐齐哈尔市第二医院儿科!161006,黑龙江齐齐哈尔市第二医院儿科!161006,黑龙江齐齐哈尔市第二医院
• 出 处: 新生儿科杂志
• 发表日期: 1995年06期
• 关键词: 脑活素 功能代谢 重度窒息 缺氧缺血性脑病 新生儿科 窒息患儿 颅内出血 计学 颅压增高 性统

报道单用胞二磷胆碱（甲组）或联合应用脑活素及胞二磷胆碱（乙组）治疗新生儿缺氧缺血性脑病，与对照组（支持、对症治疗组）比较，在临床症状消失，新生儿反射恢复上，明显优于对照组。甲、乙两组总有效率分别为85．0％和93．6％，对照组为67．1％，有显著性统计学差别。它们通过自身复杂的组成成分，直接间接影响脑的各种代谢功能，使缺氧所致脑功能代谢紊乱得以改善。在治疗新生儿缺氧缺血性脑病中近期疗效显著。

Reported single citicoline (group A) or combination of cerebrolysin and citicoline (group B) treatment of neonatal hypoxic-ischemic encephalopathy, compared with the control group (support, symptomatic treatment group) Disappeared in clinical symptoms, neonatal reflex recovery, significantly better than the control group. The total effective rates of group A and group B were 85.0% and 93.6% respectively, and 67.1% in the control group, with significant statistical difference. Through their own complicated components, they directly and indirectly affect various metabolic functions of the brain, so as to improve the disorder of brain function and metabolism caused by hypoxia. In the treatment of neonatal hypoxic-ischemic encephalopathy in the recent curative effect.