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目的全面了解和掌握广州市各区、县级市人群麻疹抗体水平,为实施有效的控制预防及消除麻疹提供科学依据。方法2008年在广州市12个区、县级市中随机抽取9个区、县级市,采集孕妇、新生儿及0岁以上11个年龄组的健康人群静脉血各40人份,采用酶标ELISA法检测麻疹IgG抗体。结果调查4043名健康者,其中抗体阳性2856人,阳性率为70.64%。所调查的9个区(县级市)中,不同区(县级市)之间的麻疹抗体阳性率差别有统计学意义(χ2=400.313,P<0.05);12岁以上组则明显下降,各年龄组之间抗体阳性率差别有统计学意义(χ2=267.832,P<0.05)。结论应加强计划免疫工作,使整个人群的免疫水平达到一个稳定的水平;在一定年龄组加强免疫接种是进一步控制麻疹爆发和流行的有效措施。
Objective To comprehensively understand and grasp the level of measles antibody among people in all districts and counties of Guangzhou and provide a scientific basis for effective prevention and elimination of measles. Methods In 2008, 9 districts and county-level cities were randomly selected from 12 districts and county-level cities in Guangzhou. Blood samples were collected from pregnant women, newborns and healthy subjects over the age of 0 and above in each of the 40 age groups. Enzyme markers Measles IgG antibodies by ELISA. Results 4043 healthy people were investigated, of which 2856 were positive, the positive rate was 70.64%. The positive rates of measles antibody in different districts (county-level cities) among the 9 districts (county-level cities) were statistically different (χ2 = 400.313, P <0.05) The positive rate of antibody between different age groups was statistically significant (χ2 = 267.832, P <0.05). Conclusion Intensive immunization should be planned so that the immunization level of the entire population will reach a stable level. Strengthening immunization in certain age groups is an effective measure to further control the outbreak and spread of measles.