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目的:探索盐酸氨溴索注射液两种不同给药途径治疗儿科呼吸系统疾病的临床疗效和不良反应。方法:将选取的166例患儿随机分成观察组和对照组两组,观察组在常规治疗的基础上使用盐酸氨溴索注射液静脉滴注进行治疗,对照组在常规治疗的基础上使用盐酸氨溴索注射液加生理盐水剂雾化吸入进行治疗。结果:观察组总有效率为97.59%;对照组总有效率为89.16%。两组总有效率比较(χ2=4.771,P=0.029)差异有统计学意义(P<0.05);观察组患儿的咳嗽咳痰、哮喘、呼吸困难、肺部啰音消失时间均显著短于对照组患儿,两组相比较差异有统计学意义(均P<0.05)。结论:盐酸氨溴索注射液静脉滴注的给药途径方法疗效比较好,临床治疗中推荐使用。
Objective: To explore the clinical efficacy and side effects of two different routes of administration of ambroxol hydrochloride injection in the treatment of pediatric respiratory diseases. Methods: The selected 166 children were randomly divided into observation group and control group. The observation group was treated with intravenous ambroxol hydrochloride injection on the basis of routine treatment. The control group was treated with hydrochloric acid Ambroxol injection plus saline saline inhalation for treatment. Results: The total effective rate was 97.59% in observation group and 89.16% in control group. The total effective rate (χ2 = 4.771, P = 0.029) in the two groups was statistically significant (P <0.05). The cough, sputum, asthma, dyspnea, and the disappearance of pulmonary rales in the observation group were significantly shorter The control group of children, the difference between the two groups was statistically significant (P <0.05). Conclusion: The administration method of intravenous infusion of ambroxol hydrochloride injection is relatively effective and is recommended for clinical treatment.