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目的探讨矮身材儿童的病因构成及与性别的关系,为临床诊治提供参考依据。方法对175例诊断为矮身材的儿童的病因进行回顾性分析。结果 175例矮身材儿童中男119例,前4位疾病分别是生长激素缺乏症(GHD)(37.8%)、部分性生长激素缺乏症(PGHD)(30.3%)、特发性矮小(ISS)(21.0%)、体质性青春期发育延迟(CDGP)(3.4%);女56例,前4位疾病分别是GHD(32.1%)、ISS(23.2%)、PGHD(21.4%)、Turner综合征(12.5%)。结论引起儿童身材矮小病因多种多样,以GHD最为常见,矮身材儿童性别不同,病因构成亦不相同。
Objective To investigate the etiology and sex of short stature children and to provide reference for clinical diagnosis and treatment. Methods Retrospective analysis of the etiology of 175 children diagnosed as short stature. Results There were 119 males and 175 females with short stature. The first four diseases were GHD (37.8%), PGHD (30.3%), idiopathic short stature (ISS) (21.0%), constitutional puberty retardation (CDGP) (3.4%); 56 women, the first four diseases were GHD (32.1%), ISS 12.5%). Conclusions The causes of dwarfism in children are diverse and the most common are GHDs. The short stature children have different sexes and different etiologies.