论文部分内容阅读
目的 :研究经验方芪龙方防治胃癌癌前疾病及其在胃癌发生发展中的作用。方法 :用 N-甲基 - N′-硝基 -N-亚硝基胍 ( MNNG)诱发新生大鼠胃癌癌前疾病及胃癌的动物模型 ,观察芪龙方对模型动物的病理组织学作用。结果 :芪龙方能显著减少 MNNG诱发的大鼠胃粘膜慢性萎缩性胃炎、胃粘膜异型增生和胃腺癌的发生率 ,与单纯病理模型组比较 P <0 .0 5 ,并呈现一定的剂量效应关系。结论 :芪龙方有较强的防治胃癌癌前病变和胃癌发生发展的作
Objective: To study the experience of Fang Fang Long Fang in the prevention and treatment of precancerous gastric cancer and its role in the development of gastric cancer. METHODS: Animal models of gastric precancerous lesions and gastric cancer were induced in neonatal rats with N-methyl-N’-nitro-N-nitrosoguanidine (MNNG) and the histopathological effects of Qi Long Fang on model animals were observed. RESULTS: Qilong prescription can significantly reduce the incidence of chronic atrophic gastritis, gastric dysplasia, and gastric adenocarcinoma induced by MNNG in rats. Compared with the simple pathological model group, P<0.05 showed a certain dose effect. relationship. Conclusion : Qi Long Fang has strong prevention and treatment of precancerous lesions of gastric cancer and the development of gastric cancer