河北省邢台市学龄前儿童单纯性肥胖与血脂异常流行现状的调查分析

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目的 对邢台市学龄前儿童单纯性肥胖与血脂异常的流行现状进行调查分析,为预防与控制提供依据.方法单纯性肥胖的判定采用2006年WHO推荐的身高体重标准,排除因内分泌等疾病引发的肥胖,凡体重≥120%者既判定为单纯性肥胖.血脂异常的判定按照胡亚美等主编的实用儿科学第7版血液生化检验正常值标准.甘油三酯 (TG) 和总胆固醇 (TC) 采用酶比色法,高密度脂蛋白胆固醇 (HDL-C) 采用选择性抑制法,低密度脂蛋白胆固醇 (LDL-C) 采用选择性清除法.检测结果中有一项超标即判定为血脂异常.结果 单纯性肥胖患病率8.20%,小、中、大班各班级男童与女童单纯性肥胖患病率的差异均无统计学意义 (χ2=0.266、0.259、0.108,P=0.606、0.611、0.742).血脂异常患病率9.84%,各班男童与女童血脂异常患病率差异均无统计学意义 (χ2=0.101、0.088、0.074,P=0.751、0.767、0.786).体重指数正常男童和女童与单纯性肥胖男童和女童血脂异常患病率的差异均有统计学意义 (χ2=935.061、862.151,P=0.000、0.000).而在体重指数正常男童与女童血脂异常患病率的差异和单纯性肥胖男童与女童血脂异常患病率的差异均无统计学意义 (χ2=0.083、0.076,P=0.773、0.783).结论 单纯性肥胖与血脂异常的发生密切相关,预防血脂异常首先要控制单纯性肥胖.“,”Objective To investigate and analyze the epidemic status of simple obesity and dyslipidemia among preschool children in Xingtai and to provide evidence for the prevention and control. Methods The standard of height and weight recommended by WHO in 2006 was used to determine simple obesity. Excluding the obesity caused by endocrine diseases, those whose weight was more than 120% were judged as simple obesity. Dyslipidemia was determined by the 7 th edition of normal value standard of blood biochemical test in Practical Pediatrics mainly edited by HU YM and other editors. Triglyceride (TG) and total cholesterol (TC) were determined by enzyme colorimetric method. High density lipoprotein cholesterol (HDL-C) was determined by selective inhibition method and low density lipoprotein cholesterol (LDL-C) was determined by selective scavenging method. Once one of the test results exceeded the standard, the patient was judged as dyslipidemia. Results The prevalence of simple obesity was 8. 20% and the difference in the prevalence of simple obesity between boys and girls in each class showed no statistical significance (χ2= 0. 266, 0. 259, 0. 108, P = 0. 606, 0. 611, 0. 742). The prevalence of dyslipidemia was 9. 84% and the difference in the prevalence of dyslipidemia between boys and girls in each class showed no statistical significance (χ2= 0. 101, 0. 088, 0. 074, P = 0. 751, 0. 767, 0. 786). The prevalence of dyslipidemia in boys and girls with normal body mass index was different from those with simple obesity. The difference was statistically significant (χ2= 935. 061, 862. 151, P = 0. 000, 0. 000). However, the difference in the prevalence of dyslipidemia between boys and girls with normal body mass index and those with simple obesity showed no statistical significance (χ2= 0. 083, 0. 076, P = 0. 773, 0. 783). Conclusion Simple obesity is closely related to the occurrence of dyslipidemia. Simple obesity should be controlled first to prevent dyslipidemia.
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