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目的:探讨肺血栓栓塞的发病特点、临床诊断及治疗措施。方法:56例肺血栓栓塞患者分为溶栓加抗凝组(17例)和单纯抗凝组(39例),回顾性分析2组患者的诊断、治疗过程,并通过临床症状、血气分析等指标分别评价其治疗效果。结果:56例患者治愈31例(55.4%),好转23例(41.1%),死亡2例(3.6%);总有效率96.4%。2例患者均死于急性呼吸衰竭合并休克。抗凝加溶栓与单纯抗凝2种治疗方法疗效比较差异无统计学意义(P>0.05)。结论:提高对肺栓塞的认识能够减少误诊;祛除易患因素,对有溶栓指征患者尽早溶栓,溶栓后序贯应用低分子肝素、华法林抗凝治疗,可提高治疗效果。
Objective: To investigate the incidence of pulmonary thromboembolism, clinical diagnosis and treatment measures. Methods: Fifty-six patients with pulmonary thromboembolism were divided into thrombolytic and anticoagulation group (n = 17) and anticoagulation group (n = 39). The diagnosis and treatment of two groups were retrospectively analyzed. The clinical symptoms and blood gas analysis Indicators were evaluated for the treatment effect. Results: 56 cases were cured in 31 cases (55.4%), improved in 23 cases (41.1%) and died in 2 cases (3.6%). The total effective rate was 96.4%. Both patients died of acute respiratory failure with shock. The anticoagulant plus thrombolytic therapy and simple anticoagulation two kinds of treatment methods were no significant difference in efficacy (P> 0.05). Conclusion: To improve the understanding of pulmonary embolism can reduce the misdiagnosis; eliminate the predisposing factors, thrombolytic indications for patients as soon as possible thrombolysis, thrombolysis sequential application of low molecular weight heparin, warfarin anticoagulant therapy can improve the therapeutic effect.