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目的探讨6min步行距离与COPD患者的肺功能、症状严重程度、生活质量的相关性，对患者病情的评估价值。方法对纳入COPD稳定期患者60例患者进行6min步行试验，收集患者的基本资料、第1s用力呼气量(FEV1)占预计值的百分比、mMRCD评分、CAT评分、圣乔治呼吸问卷和SF-36生活质量量表评分，分别进行单因素及多因素的相关性分析。结果单因素分析显示COPD患者的6min步行距离分别与FEV1占预计值的百分比、mMRCD评分、CAT评分、SGRQ评分、SF-36生活质量量表评分之间有相关性(<0.05)。经多重线性逐步回归分析，mMRCD评分、SGRQ评分与患者的6min步行距离仍具有显著的相关性(<0.001)。合并肺动脉高压的COPD患者，6min步行距离显著低于未合并肺动脉高压的患者(<0.05)。结论6min步行试验与COPD患者的肺功能、症状严重程度、生活质量具有显著相关性，且操作简便、安全、实用，可作为一种长期的日常监测手段。“,”Objective To explore the associations between six-minute walk test and lung function,severity of dyspnea,quality of life in patients with COPD.Methods All patients were tested with six-minute walk test.The basic information,FEV1%predicted,mMRCD score,CAT score,SGRQ score and SF-36 scale were recorded.The univariate analysis and multivariate analysis were performed.Results The univariate analysis showed that in patients with COPD there was a significant correlation of the six-minute walk distance with FEV1%predicted,mMRCD score,CAT score,SGRQ score and SF-36 scale.The multivariate analysis revealed the associations between the six-minute walk distance and mMRCD and SGRQ score.The COPD patients with pulmonary arterial hypertension had shorter six-minute walk distance ( <0.05).Conclusion The six-minute walk test can help to evaluate the illness severity of patients with COPD,which is a practical tool for patients to monitor the disease in daily life.