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By means of light and electron microscopy and texture analysissystem, the morphologic changes and the content of DNA after injection ofhematoporphyrin derivatives (HPD) in different pathways and the lightirradiation on mice H_(22) hepatoma were observed. This study showed thatintravenous injection of HPD and local administration in the tumor andred-light irradiation could result in obvious injury of tumor cells, especiallythe tumor local injection and light irradiation. In order to reduce variousside-effects, tumor local injection and light irradiation may be used inclinical treatment. This article provides morphological basis for reference.
By means of light and electron microscopy and texture analysissystem, the morphologic changes and the content of DNA after injection of hematoporphyrin derivatives (HPD) in different pathways and the lightirradiation on mice H_ (22) hepatoma were observed. This study showed that intravenous injection of HPD and local administration in the tumor andred-light irradiation could result in obvious injury of tumor cells, especially the tumor local injection and light irradiation. basis for reference.