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近十年中枢神经系统(CNS)白血病的诊断有明显的增加,由于它是阻碍长期缓解、影响存活时间和减少治疗机会的重要因素,所以是当前白血病治疗的重要课题之一。但国内报道尚少,故对其发病率和诊治问题做一综述。一、CNS白血病的发病率和影响其出现的因素。自从Burns1823年首次报告白血病的神经系统合并症以来,文献屡有报道,尤其是CNS白血病的发病率不断增加。Evans分析了1947—1960年十四年中的921例儿童白血病,发现CNS白血病发病率1947—1954年为4%,而
The diagnosis of central nervous system (CNS) leukemia in recent ten years has been significantly increased. It is one of the most important topics in the current treatment of leukemia because it is an important factor that hinders long-term remission, affects survival time and reduces opportunities for treatment. However, there are still few domestic reports, so its morbidity and diagnosis and treatment are reviewed. First, the incidence of CNS leukemia and the factors that affect its emergence. Since the first report of Burns in 1823, the prevalence of leukosis has been reported in the literature, especially in the growing incidence of CNS leukemia. Evans analyzed 921 childhood leukemias in fourteen years from 1947 to 1960 and found that the incidence of CNS leukemia was 4% from 1947 to 1954, while