论文部分内容阅读
目的探讨妊娠高血压综合征(妊高症)采用硫酸镁与硝苯地平联合治疗的临床效果。方法 100例妊高症患者,随机分为对照组和观察组,各50例。对照组单用硫酸镁治疗,观察组在此基础上加用硝苯地平治疗。比较两组患者治疗效果。结果观察组总有效率为96%,高于对照组的70%(P<0.05)。治疗后观察组收缩压为(133.5±11.3)mm Hg(1 mm Hg=0.133 k Pa),舒张压为(79.1±6.3)mm Hg,24 h尿蛋白定量为(1.1±0.2)g;对照组收缩压为(141.6±12.4)mm Hg,舒张压为(85.2±5.7)mm Hg,24 h尿蛋白定量为(1.9±0.2)g,观察组均明显低于对照组,差异具有统计学意义(P<0.05)。观察组不良反应发生率为6%,对照组为8%,比较差异无统计学意义(P>0.05)。结论针对临床收治的妊高症患者,采用硫酸镁联合硝苯地平治疗,可显著提高临床效果,控制血压,且具较高安全性,对保障预后价值显著。
Objective To investigate the clinical effect of combined treatment of magnesium sulfate and nifedipine in pregnancy-induced hypertension syndrome (pregnancy-induced hypertension). Methods 100 patients with pregnancy induced hypertension were randomly divided into control group and observation group, 50 cases each. The control group was treated with magnesium sulfate alone, and the observation group was treated with nifedipine on the basis of this. Compare the treatment effect of two groups of patients. Results The total effective rate was 96% in the observation group, which was higher than 70% in the control group (P <0.05). After treatment, the systolic blood pressure of the observation group was (133.5 ± 11.3) mm Hg (1 mm Hg = 0.133 k Pa), the diastolic blood pressure was (79.1 ± 6.3) mm Hg and the urine protein of 24 h was (1.1 ± 0.2) Systolic blood pressure was (141.6 ± 12.4) mm Hg, diastolic pressure was (85.2 ± 5.7) mm Hg, and urine protein of 24 h was (1.9 ± 0.2) g. The observation group was significantly lower than that of the control group P <0.05). The incidence of adverse reactions in the observation group was 6% and in the control group was 8%, with no significant difference (P> 0.05). Conclusions The treatment of pregnancy induced hypertension with magnesium sulfate combined with nifedipine can significantly improve the clinical effect, control blood pressure, and with high safety, the prognostic value of the protection of significant.