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目的探讨宫颈上皮内瘤变Ⅱ~Ⅲ级行宫颈环形电切除术(利普刀,LEEP)或冷刀(CKC)的疗效,寻求宫颈上皮内瘤变的更好监测手段。方法 2010-01/2011-01在中国人民解放军第303医院妇科,采集64例宫颈上皮内瘤变Ⅱ~Ⅲ级患者样本,术前确诊并除外宫颈浸润癌,随机分成2组,34例行LEEP,30例行CKC锥切术,进行2组手术时间、术中出血量、医疗费用和疗效对比。结果利普刀切除术手术时间、术中出血、医疗费用等方面均少于冷刀锥切组,差异有统计学意义(P<0.05),2组术后病检和疗效差异无统计学意义(P>0.05)。结论利普刀操作简便,手术时间短,术中出血量少,费用低,治愈率高,是目前较理想的治疗方法。
Objective To investigate the curative effect of cervical ring electrosurgical resection (LEEP) or cold knife (CKC) in cervical intraepithelial neoplasia grade Ⅱ ~ Ⅲ, and to find a better monitoring method for cervical intraepithelial neoplasia. METHODS: From January 2010 to January 2011, 64 samples of cervical intraepithelial neoplasia patients with stage Ⅱ ~ Ⅲ were collected from the Department of Gynecology, the 303 Hospital of the Chinese People’s Liberation Army. The patients were diagnosed with cervical invasive carcinoma before operation and were randomly divided into two groups. 34 patients underwent LEEP , 30 cases of CKC conization, operation time of 2 groups, intraoperative blood loss, medical costs and efficacy comparison. Results Lipopectomy surgery time, intraoperative bleeding, medical costs, etc. were less than the cold knife conization group, the difference was statistically significant (P <0.05), postoperative pathological examination and the two groups showed no statistically significant difference (P> 0.05). Conclusion Lipps knife is simple and convenient operation, short operative time, less blood loss, low cost and high cure rate, which is an ideal treatment method.