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目的探讨肺炎支原体(Mp)、肺炎衣原体(Cpn)感染与儿童慢性咳嗽(CC)的关系。方法对确诊的128例儿童慢性咳嗽和120名对照组儿童采用ELISA方法检测血浆Mp、Cpn特异性IgM抗体,并进行组间比较。结果研究组与对照组Mp、Cpn感染情况分别是:Mp感染52例(40.63%),对照组18例(15.0%);Cpn感染47例(36.72%),对照组13例(10.83%);混合感染分别是4例(3.12%),对照组0例。两组比较差异有统计学意义。结论肺炎支原体、衣原体感染与小儿慢性咳嗽关系密切,临床应采用针对性治疗。
Objective To investigate the relationship between Mycoplasma pneumoniae (Mp), Chlamydia pneumoniae (Cpn) infection and childhood chronic cough (CC). Methods A total of 128 children with chronic cough and 120 controls were enrolled in this study. Plasma Mp and Cpn specific IgM antibodies were detected by ELISA and compared between groups. Results The infection rates of Mp and Cpn in study group and control group were Mp infection in 52 cases (40.63%), control group (18 cases) in 15.0 cases, Cpn infection in 47 cases (36.72%) and control group (13 cases) Mixed infections were 4 cases (3.12%) and 0 cases in the control group. The difference between the two groups was statistically significant. Conclusions Mycoplasma pneumoniae and Chlamydia infection are closely related to chronic cough in children, and targeted therapy should be used clinically.