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目的探讨外周血中炎性标志物血清C反应蛋白水平变化与胃癌化疗的关系。方法分析河南大学淮河医院肿瘤内科自2008年到2009年接诊的晚期胃癌患者的C反应蛋白水平,了解化疗前及化疗后1周、2周及化疗2周期后血清C反应蛋白的变化。结果化疗有效患者的CRP水平化疗后早期明显下降,无效组患者的差别不明显。结论 CRP对肿瘤的近期治疗有重要监测意义。
Objective To investigate the relationship between serum C-reactive protein level in peripheral blood inflammatory markers and gastric cancer chemotherapy. Methods The levels of C-reactive protein in patients with advanced gastric cancer admitted to Department of Oncology, Huaihe Hospital, Henan University from 2008 to 2009 were analyzed to understand the changes of serum C-reactive protein before and after 1 week, 2 weeks and 2 cycles of chemotherapy. Results The level of CRP in chemotherapy-effective patients decreased significantly in the early period after chemotherapy, while the difference in patients in the invalid group was not obvious. Conclusion CRP has important significance in the short term treatment of tumor.