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目的探析采用小剂量肝素配伍舒喘灵治疗妊娠合并子宫肌瘤红色变性患者的临床效果以及安全性。方法将我院2005年8月-2011年12月间60例患者随机分为治疗组和对照组各30例,分析对比两组患者住院期间以及随访的资料。结果治疗组未出现由于子宫肌瘤红色变性导致的早产和流产,也未出现单纯行急诊子宫肌瘤切除术的患者,抑制宫缩保胎的疗效明显优于对照组(P<0.05),健康存活儿出生率明显高于对照组(P<0.05);临床症状明显改善的时间明显短于对照组(P<0.05),两组患者在治疗期间未见凝血功能异常。结论对妊娠合并子宫肌瘤红色变性患者采用小剂量肝素配伍舒喘灵治疗方案疗效确切,明显提高健康存活儿的出生率,同时避免了使用硫酸镁导致患者在治疗期间长时间输液的不适感,安全有效,可作为首选治疗方案,值得临床推广应用。
Objective To investigate the clinical efficacy and safety of low-dose heparin with salbutamol in patients with red degeneration of uterine fibroids during pregnancy. Methods Sixty patients in our hospital from August 2005 to December 2011 were randomly divided into treatment group (30 cases) and control group (30 cases). The data of two groups were compared during hospitalization and follow-up. Results The treatment group did not appear due to red degeneration of uterine fibroids caused by premature birth and abortion, and no simple line of emergency myomectomy patients, the effect of inhibiting tocolysis was significantly better than the control group (P <0.05), healthy The birth rate of survivors was significantly higher than that of the control group (P <0.05). The time for improvement of clinical symptoms was significantly shorter than that of the control group (P <0.05). No coagulation dysfunction was found in the two groups during the treatment. Conclusion The treatment of red degeneration with uterine fibroids in pregnant women with low-dose heparin and shuzhouling treatment regimen curative effect, significantly improve the birth rate of healthy survivors, while avoiding the use of magnesium sulfate causes patients to prolonged infusion of discomfort during treatment, safety Effective, can be used as the preferred treatment options, it is worth clinical application.