论文部分内容阅读
应用双抗体夹心法检测了５４例慢性乙型肝炎、肝硬化患者血清可溶性白介素２受体（ＳＩＬ－２Ｒ），应用单克隆抗体和ＡＰＡＡＰ法对Ｔ淋巴细胞亚群进行了检测，结果示慢性乙型肝炎病人血清ＳＩＬ－２Ｒ明显高于对照组，并且其升高与血清胆红素水平相关，而病人ＯＫＴ３细胞与正常对照组无显著差异，ＯＫＴ４阳性细胞比例下降，ＯＫＴ８阳性细胞比例增加，ＯＫＴ／ＯＫＴ比值下降，各临床类型中以重症肝炎ＯＫＴ／ＯＫＴ比值下降显著，其次为慢活肝，说明随着肝细胞坏死程度加重，免疫紊乱状态更加严重。
Serum soluble interleukin-2 receptor (SIL-2R) was detected in 54 patients with chronic hepatitis B and cirrhosis by double antibody sandwich method. T lymphocyte subsets were detected by monoclonal antibody and APAAP assay. The results showed that chronic hepatitis B The serum level of SIL-2R in patients with hepatitis was significantly higher than that in control group, and the level of serum SIL-2R was correlated with the level of serum bilirubin. There was no significant difference between OKT3 cells and normal controls, the percentage of OKT4 positive cells decreased, the percentage of OKT8 positive cells increased, / OKT ratio decreased in all clinical types of severe hepatitis OKT / OKT ratio decreased significantly, followed by slow living liver, indicating that as the degree of liver cell necrosis aggravated, immune disorder is more serious.