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作者提出在精神病治疗中,氯丙嗪类是常用的药物。但有些病人对这类药物过敏,用最小剂量,也发生中毒反应。甚至引起中毒——变态反应性肝炎(可致急性肝萎缩),大疱性皮炎或过敏性休克,突然死亡,死因在某些病例可能是坏死性肾炎、血栓形成、栓塞、卒中等。作者设计了一种过敏实验的方法,其具体操作如下:用2.5%氯丙嗪注射剂,稀释50倍,给病人一次前臂内侧皮内注射0.025—0.05毫克氯丙嗪(0.05～0.1毫升稀释液——编者),以蒸溜水注射对照(另用注射器与针头),观察40分钟,无反应者为阴性。阳性反应者十分钟后皮肤开始发红、
The authors suggest that chlorpromazine is a commonly used drug in psychiatric treatment. However, some patients allergic to these drugs, with the minimum dose, but also toxic reactions. Even poisoning - allergic hepatitis (can cause acute liver atrophy), bullous dermatitis or anaphylactic shock, sudden death, in some cases the cause of death may be nephritis, thrombosis, embolism, stroke and so on. The authors devised an allergy test by performing a 50-fold dilution of a 2.5% chlorpromazine injection into the medial forearm of the patient and injecting 0.025-0.05 milligrams of chlorpromazine (0.05-0.1 milliliters of diluent- - Editor), distilled water injection control (another syringe and needle), observed for 40 minutes, non-responders were negative. Positive reaction ten minutes after the skin began to redness,