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目的为探讨新生儿硬肿症并发消化道穿孔的发病规律。方法通过对２１例患儿进行临床观察，分析病情变化相关的因素。结果９例未手术全部死亡，手术１２例，仅３例存活，发现新生儿硬肿症并发消化道穿孔与硬肿程度、早产、并发其他严重疾病密切相关，使用激素、护理不当亦可促使发病。结论认为新生儿硬肿症并消化道穿孔，尽量不用激素，发现穿孔应立即手术治疗。
Objective To explore the pathogenesis of neonatal sclerema complicated with digestive tract perforation. Methods 21 cases of children through clinical observation, analysis of changes in disease-related factors. Results All 9 patients died without surgery. Only 12 patients survived. Only 3 patients survived. The incidence of neonatal scleredema complicated by perforation of the digestive tract and degree of sclerosis, premature delivery and other serious diseases was found. The use of hormones and improper care also contributed to the onset . Conclusions that neonatal sclerosing and digestive tract perforation, try not to use hormones and found that perforation should be treated immediately.