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子宫内膜异位症是一种与不孕症相关的妇科常见病,大量研究表明免疫学变化在该病的病理生理学中具有重要的作用,患者常伴有细胞和体液免疫功能异常。而在体液免疫中,除子宫内膜抗体外,在患者的异位灶、外周血和腹腔液中非器官特异性抗体也多有表达,如抗磷脂抗体。本文采用酶联免疫吸附试验对子宫内膜异位症患者外周血进行抗心脂抗体(ACL,抗磷脂抗体的一种)的测定,通过对照分析,对其发病机理及治疗方法进行探讨。 资料与方法 一、对象 将研究对象分为3组:①子宫内膜异位症组:年龄26～43岁,为本院及天津市妇幼保健院的就诊患者,经剖腹探查或腹腔镜检查或病理确证患子宫内
Endometriosis is a common gynecological disease associated with infertility, a large number of studies have shown that immunological changes play an important role in the pathophysiology of the disease, patients often associated with abnormal cellular and humoral immune function. In humoral immunity, in addition to endometrial antibodies, in patients with heterotopic foci, peripheral blood and peritoneal fluid non-organ specific antibodies are also more expression, such as anti-phospholipid antibodies. In this study, enzyme-linked immunosorbent assay for peripheral blood in patients with endometriosis anti-lipid antibodies (ACL, an anti-phospholipid antibodies) determination by control analysis of its pathogenesis and treatment. Materials and Methods 1. Subjects The subjects were divided into three groups: ① endometriosis group: aged 26 to 43 years, for the hospital and Tianjin MCH pediatric patients, laparotomy or laparoscopy or Pathologically confirmed intrauterine