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众所周知,患胆石症的人大多为女性,而这些妇女多数肥胖。但胆石症也发生于非肥胖妇女的原因不明,可能的解释是肠排空缓慢。1987～1989年在英国布里斯托尔,对1058例(25～69岁)妇女进行了胆囊造影。48例发现胆结石,其中15例体重正常(体重指数≤25kg/m~2)。这15例妇女中,25～29岁2例,30～39岁5例,40～49岁3例,50～59岁2例,60～69岁3例。这些妇女与同龄健康胆囊者均行消化道排空时间(WGTT)测定,患胆石妇女的WGTT比对照组平均长19小时,对照组的排空时间与校准年龄正常体重妇女的群体很类似。胆石症者24小时排便量也少,10例胆石症正常体重妇女的24小时平均大便量为74g,同龄对照组平均141g,平均相差65g(P=0.015)。病例与对照组在体重指数、腰—臀围比率、经产
It is well-known that most people suffering from cholelithiasis are women, and most of these women are obese. However, the cause of cholelithiasis also occurs in non-obese women is unknown, the possible explanation is slow bowel emptying. From 1987 to 1989 in Bristol, England, 1058 women (25-69 years old) underwent cholecystography. 48 cases found gallstones, of which 15 cases of normal weight (body mass index ≤ 25kg / m ~ 2). Among the 15 women, 25 were 29 years old, 2 cases were 30 to 39 years old, 3 cases were 40 to 49 years old, 2 cases were 50 to 59 years old and 3 cases were 60 to 69 years old. The WGTT was measured in all women and those with healthy gall bladder at the same age. The WGTT of women with gallstone was longer than the control group by an average of 19 hours. The control group had a similar emptying time to that of normal-weight women of normal age. Patients with cholelithiasis also had a small amount of defecation in 24 hours. The average stool volume of 24 women in 10 normal cholelithiasis women was 74 g, with an average of 141 g in the same age group, with an average difference of 65 g (P = 0.015). Cases and control group in the body mass index, waist - hip ratio, by the production