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目的:探讨胃癌VEGF-C表达与MSCT表现的关系。方法:对48例胃癌患者术前1周行MSCT平扫及增强扫描,术后应用免疫组织化学染色法检测胃癌组织VEGF-C的表达。结果:CT图像显示的肿瘤强化幅度≥30HU组VEGF-C阳性表达率(91.3%)明显高于强化幅度<30HU组(52.0%),有浆膜侵犯组VEGF-C阳性表达率(87.1%)明显高于无浆膜侵犯组(41.2%),淋巴结转移组VEGF-C阳性表达率(81.6%)高于无淋巴结转移组(30.0%),P均<0.05。结论:胃癌组织VEGF-C表达与CT图像显示的胃癌强化幅度、浸润深度、淋巴结转移相关。
Objective: To investigate the relationship between VEGF-C expression and MSCT in gastric cancer. Methods: Forty-eight patients with gastric cancer underwent MSCT scan and enhanced scan one week before operation. The expression of VEGF-C in gastric cancer tissues was detected by immunohistochemistry after operation. Results: The positive rate of VEGF-C expression in CT group was significantly higher than that in 30HU group (91.3%) than that in 30HU group (52.0%). The positive rate of VEGF-C expression in serosa invasion group was 87.1% The positive rate of VEGF-C expression in lymph node metastasis group was significantly higher than that in non-lymph node metastasis group (41.2% vs 81.0%, P <0.05). Conclusion: The expression of VEGF-C in gastric carcinoma is related to the enhancement of gastric cancer, depth of invasion and lymph node metastasis in CT images.