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目的:通过对原发性肝癌手术后复发的血管造影、介入治疗和复发原因的探讨,以期提高肝癌术后复发的诊断、治疗和预防。方法:分析142例复发病例,详细观察术前肿瘤大小、数量、大体病理或显微病理所见、复发肿瘤的时间、大小、数量、血供、染色和碘油沉积等情况。所有患者在造影后即行动脉内灌注化疗药物、碘油和/或明胶海绵栓塞。结果:原发肿瘤大于5cm者101例(71.12%),小于5cm者41例(28.87%);原发肿瘤包膜不完整和无包膜者96例(67.61%)。术中发现肿瘤旁子灶47例(33.1%),门静脉癌栓26例(18.31%)。病理中发现子灶94例(66.2%),门静脉癌栓121例(85.21%)。术后6个月以内复发者99例(69.72%)。复发多为小于5cm的多发性结节97例(68.31%)。肿瘤血供丰富者100例(70.42%)。TAE后碘油沉积良好者93例(65.49%)。结论:原发性肝细胞癌大于5cm、无包膜或包膜不完整、有卫星灶和门静脉癌栓者手术后复发率高;复发的肿瘤多呈小于5cm的多发性结节,但也可呈巨块型;复发灶血供多丰富且介入治疗碘油沉积良好。肝癌具有单克隆(单中心)和多克隆(多中心)两种起源形式,同?
Objective: To explore the causes of angiography, interventional therapy and recurrence after reoperation of primary liver cancer in order to improve the diagnosis, treatment and prevention of postoperative recurrence of liver cancer. Methods: Analysis of 142 cases of recurrent cases, detailed observation of the size of the preoperative tumor, the number of gross pathological or microscopic pathological findings, the time, size, number of recurrent tumors, blood supply, staining and lipiodol deposition. All patients were intraarterially infused with chemotherapeutic drugs, lipiodol, and/or gelatin sponge embolizations after contrast. Results: 101 cases (71.12%) were primary tumors larger than 5cm, 41 cases (28.87%) were smaller than 5cm, and 96 cases (67.61%) were incomplete tumor capsules and primary tumors. During the operation, 47 cases (33.1%) of paraneoplastic foci and 26 cases (18.31%) of portal vein tumor emboli were found. 94 cases (66.2%) of sub-foci were found in pathology, and 121 cases (85.21%) of portal vein tumor thrombi were found. 99 cases (69.72%) recurred within 6 months after operation. Most of the relapses were less than 5cm in 97 cases (68.31%) of multiple nodules. 100 patients with abundant blood supply (70.42%). After TAE, 93 cases (65.49%) had good lipiodol deposition. CONCLUSIONS: The primary hepatocellular carcinoma is more than 5 cm in size, with no capsule or incomplete capsules, and with satellite and portal vein tumor thrombi; the recurrence rate is high after surgery; recurrent tumors are mostly multiple nodules less than 5 cm, but they can also be It was massive; recurrent blood supply was more abundant and interventional treatment of lipiodol deposition was good. Liver cancer has a single (monocentric) and polyclonal (multi-center) forms of origin, and the same?