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目的 :探讨 型糖尿病 (2 - DM)患者视网膜中央动脉 (CRA)的血流动力学变化及与糖化血红蛋白水平之间的关系。方法 :应用彩色多普勒血流显像 (CDFI)对 84例 (16 8眼 ) 型糖尿病患者的视网膜中央动脉进行检测 ,经眼底检查确定有无合并视网膜病变并对合并视网膜病变者进行分型 ,同时检测其糖化血红蛋白的水平。结果 :1.糖尿病各组 CRA的 Vs、 Vd均低于正常对照组 (P<0 .0 5 ) ;RI高于对照组 (P<0 .0 5 ) ;2 .经相关性分析表明 Hb A1c与 型糖尿病患者 CRA的血流速度测值呈负相关 ,与 CRA的 RI呈正相关。结论 :血糖是影响视网膜血流变化的重要因素之一。 CDFI是评价 CRA血流动力学变化的有效方法。
Objective: To investigate the relationship between the hemodynamic changes of central retinal artery (CRA) and the level of HbA1c in patients with type 2 diabetes mellitus (DM). Methods: The central retinal artery of 84 patients (168 eyes) with diabetes mellitus was examined by color Doppler flow imaging (CDFI). The fundus examination was used to determine the presence or absence of retinopathy and to classify the patients with retinopathy , While detecting the level of glycosylated hemoglobin. Vs and Vd of CRA in each group were lower than those in normal control group (P <0.05); RI was higher than that in control group (P <0.05); 2. Correlation analysis showed that Hb A1c There was a negative correlation between the blood flow velocity of CRA and the RI of CRA in type 2 diabetic patients. Conclusion: Blood glucose is one of the important factors affecting the retinal blood flow. CDFI is an effective method to evaluate the hemodynamic changes of CRA.