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目的探讨孕期筛查BV的安全性及治疗妊娠期BV对于围产结局的影响。方法收集于我院进行产前检查的无孕前合并症的孕妇共1000例分为筛查组800例及未筛查组200例,比较孕期流产率的差异;分别比较筛查组中BV(-)组678例与BV(+)治疗组62例和BV(+)未治疗组60例的围产结局。结果 1筛查组与未筛查组孕妇的孕期流产率差异无统计学意义(P>0.05);2BV(-)组流产、早产、胎膜早破、低出生体重儿、新生儿感染及产褥感染的发生率均低于BV(+)未治疗组,差异有统计学意义(P<0.05);3BV(-)组流产、早产、胎膜早破、低出生体重儿、新生儿感染及产褥感染的发生率均低于BV(+)治疗组,但差异无统计学差异(P>0.05)。结论孕期BV筛查不会增加流产率;妊娠合并BV会增加不良围产结局的发生;经过治疗的BV孕妇围产结局能够得到改善。
Objective To investigate the safety of screening BV during pregnancy and the effect of treating BV on perinatal outcome. Methods A total of 1000 pregnant women without preconception complications who were collected in our hospital for prenatal examination were divided into a screening group of 800 cases and a non screening group of 200 cases to compare the differences in pregnancy rate of miscarriage; ), 678 cases and BV (+) treatment group, 62 cases and BV (+) untreated group, 60 cases of perinatal outcome. Results There was no significant difference in pregnancy abortion rates between pregnant women in screening group and non-screening pregnant women (P> 0.05). The incidence of abortion, premature rupture of membranes, premature rupture of membranes, low birth weight infants and newborn infants in 2BV (- The incidence of puerperal infection was lower than BV (+) untreated group, the difference was statistically significant (P <0.05); abortion, premature labor, premature rupture of membranes, low birth weight infants, neonatal infection in 3BV (- The incidence of puerperal infection were lower than BV (+) treatment group, but the difference was not statistically significant (P> 0.05). Conclusion The screening of BV during pregnancy will not increase the miscarriage rate. Pregnancy with BV will increase the incidence of adverse perinatal outcomes. Peripheral outcomes of treated pregnant women with BV may be improved.