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为了探讨鼻咽癌放疗后颈部残留灶的最佳处理方法,收集了1986年12月至1991年12月105例资料完整的鼻咽癌放疗后颈部残留灶病例资料。15例行手术治疗,术后颈部复发率,局部控制率,5a生存率分别为6.7%,93.4%,53.3%,术后病理诊断阳性率为40.0%。27例行化学治疗,总有效率及5a生存率分别为37.0%,33.3%。手术治疗与化学治疗的5a生存率比较,差异无显著性,P>0.05。63例继续观察,6个月内颈残留灶完全消退患者与未消退者5a生存率分别为42.5%和13.0%,差异有显著性,P<0.05。鼻咽癌放疗后颈部残留灶应密切随访观察,如未消退则应积极采取补救措施,首选手术治疗,能完全消退者则不影响其5a生存率。
In order to investigate the optimal treatment of residual neck lesions after radiotherapy of nasopharyngeal carcinoma, we collected 105 cases of cervical residual disease after radiotherapy of 105 cases of nasopharyngeal carcinoma after radiotherapy from December 1986 to December 1991. Surgical treatment of 15 cases, postoperative neck recurrence rate, local control rate, 5a survival rates were 6.7%, 93.4%, 53.3%, postoperative pathological diagnosis was 40.0%. 27 routine chemotherapy, the total effective rate and 5a survival rates were 37.0%, 33.3%. There was no significant difference in the 5-year survival rate between surgical treatment and chemotherapy (P> 0.05). The survival rates of patients with complete remission of neck residual within 6 months and those without remission were 42.5% And 13.0%, the difference was significant, P <0.05. Nasopharyngeal carcinoma after neck radiotherapy should be followed up closely observed, if not subsided, should take active remedial measures, the preferred surgical treatment, can completely dissipate those who did not affect the 5a survival rate.