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目的观察胰岛素泵治疗小儿1型糖尿病的临床效果。方法将1型糖尿病患儿64例随机分为观察组和对照组各32例,观察组采用胰岛素泵治疗,对照组采用连续皮下注射胰岛素治疗,比较2组患儿的临床治疗效果与低血糖发生率。结果 2组患儿治疗后餐前平均血糖、餐后2 h平均血糖均低于治疗前,且观察组低于对照组,差异均有统计学意义(P<0.05)。观察组患儿血糖达标时间短于对照组,低血糖发生率低于对照组,差异均有统计学意义(P<0.05)。结论胰岛素泵治疗1型糖尿病患儿疗效确切,且极为安全,值得临床推广。
Objective To observe the clinical effect of insulin pump on children with type 1 diabetes. Methods Sixty-four children with type 1 diabetes were randomly divided into observation group and control group with 32 cases each. The observation group was treated with insulin pump and the control group with continuous subcutaneous injection of insulin. The clinical efficacy and hypoglycemia of two groups were compared rate. Results The mean pre-prandial glucose level, mean postprandial 2-hour postprandial blood glucose level were lower in the two groups after treatment than in the control group, and the difference was statistically significant (P <0.05). The observed time of blood glucose in observation group was shorter than control group, the incidence of hypoglycemia was lower than that of control group, the difference was statistically significant (P <0.05). Conclusion Insulin pump in children with type 1 diabetes has definite curative effect and is extremely safe. It is worthy of clinical promotion.