Significant implications of Bcl-2 in the formation of striatonigral projection neurons in the ischem

• 作 者: Dong-Ya Zhu
• 机 构: Laboratory of Cerebrovascular Disease,Key Laboratory of Cardiovascular Disease and Molecular Interve
• 出 处: Neuroscience Bulletin
• 发表日期: 2012年06期
• 关键词: projection functionally progenitor granule dentate gyrus ganglia glial nestin su

In adult mammals,including humans,the subventricular zone(SVZ) of the lateral ventricles and the subgranular zone of the dentate gyrus(DG) show ongoing neurogenesis. Cerebral ischemic insults trigger neurogenesis from neural stem cells or progenitor cells located in the SVZ and DG.Newborn neurons are then functionally recruited into the circuitry of the CA1 region,striatum and DG granule cell layer.

Cerebral ischemic insults trigger neurogenesis from neural stem cells or progenitor cells located in the SVZ and DG Newborn neurons are then functionally recruited into the circuitry of the CA1 region, striatum and DG granule cell layer.