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心脑血管疾病患者存在血管内皮功能不全，且血管内皮功能不全可能是病因以及疾患早期表现之一，而心脑血管疾患本身也加重血管内皮功能不全的发生。临床研究表明，正常的血管内皮具有保护作用，可以延缓心脑血管疾病的发生，且在发病早期，机体会出现内皮功能损伤。因此，及早进行血管内皮功能的检测并采取相应措施对心脑血管疾病的防治具有重要意义。当前，利用Endo-PAT设备可行无创血管内皮功能诊断，测定反应性充血指数在临床应用中具有重要意义。现对近年来有关血管内皮功能与反应性充血指数关系的研究作出总结，为其在临床上的更好应用提供参考依据。“,”Vascular endothelial dysfunction( VED) is the early manifestation in patients with cardiovascular and cerebrovascular dis-eases, furthermore cardiovascular disease and cerebrovascular disease itself also increase the occurrence of VED.Clinical researches show that normal vascular endothelium has protective effect, and can delay the occurrence of cardiovascular and cerebrovascular diseases, in the early stage, the body will appear endothelial dysfunction but no clinical symptoms.Therefore, early detection of vascular endothelial function and take corresponding measures to prevent cardiovascular disease have important significance.At present, the Endo-PAT equipment is used to detect vascular endothelial function noninvasively, and get the reactive hyperemia index which has important significance in clinical appli-cation.The research about the relationship between vascular endothelial function and reactive hyperemia index is summarized, which can provide reference for its clinical application.