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本文报道血管扩张剂硝普盐对严重二尖瓣关闭不全的作用。患者共8例,男7例,女1例。年龄45～69岁。病因可能是乳头肌动能失调及/或瓣环扩张,其中2例是心肌梗塞并发严重二尖瓣关闭不全。除1例外,所有患者都有心脏扩大及充血性心力衰竭的症状(持续2天～2年)。8例均示明显二尖瓣关闭不全伴有肺动脉高压的体征。胸片均示心脏扩大及肺静脉充血;3例有肺水肿。肺毛细血管楔嵌压曲线均有巨大V波。方法:硝普盐以16～100微克/分速度静
This article reports the effect of nitroprusside, a vasodilator, on severe mitral regurgitation. A total of 8 patients, 7 males and 1 female. Age 45 ~ 69 years old. Etiology may be dysplasia of the papillary muscles and / or dilatation of the annulus, two of which are complicated by severe myocardial infarction with mitral regurgitation. All but one of the patients had symptoms of enlarged heart and congestive heart failure (lasting 2 days to 2 years). 8 cases showed obvious mitral regurgitation accompanied by signs of pulmonary hypertension. Chest radiographs showed enlarged heart and pulmonary venous congestion; 3 cases had pulmonary edema. Pulmonary capillary wedge pressure curve has a huge V wave. Methods: Nitroprusside at 16-100 ug / min speed static