论文部分内容阅读
人们想到高血压的发生与儿茶酚胺、肾素等有关,而β受体阻滞剂具有特异的阻滞效应细胞特有的生理反应、膜稳定化作用(奎尼丁样作用)、固有的交感神经刺激作用(ISA)、脏器选择性四大特性。自Prichard于1964年首次报告β阻滞剂治疗高血压,十余年来,经过反复的动物试验和临床实践证明:β阻滞剂的降压作用是肯定的,在降压药物中占有相当
People think of the occurrence of hypertension with catecholamines, renin and other related, and β-blockers have a specific blocking specific effector cells physiological responses, membrane stabilization (quinidine-like effect), the inherent sympathetic stimulation (ISA), organ selectivity of the four major features. Since Prichard first reported beta blockers in 1964 for the treatment of hypertension, more than 10 years after repeated animal experiments and clinical practice proved that the antihypertensive effect of beta blockers is affirmative, occupying a considerable proportion of antihypertensive drugs