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作者在1987年8月和1988年11月将参加社区儿童保健门诊的2097名6～11月龄正常婴儿分成4组,分别接种4种不同疫苗,中等滴度和高滴度Schwarz株疫苗,中等滴度和高滴度Edmonston-Zagreb株疫苗,其中接种上述疫苗的男婴各占53.8％、49.8％、49.1％和47.2％;393名9月龄婴儿接种Schwarz株标准滴度（10~(3.0)～10~(3.7)空斑形成单位/剂）疫苗作为对照,其中男婴占50.7％。前4种疫苗的滴度比标准滴度高10倍（中等滴度）或100倍（高滴度）。 结果表明,接种高滴度Edmonston-Za-greb株疫苗的婴儿死亡率最高。接种中等滴度Schwarz株疫苗的婴儿死亡率最低;接种不同滴度或病毒株疫苗的男婴死亡率几无差别,且与接种标准滴度疫苗的婴儿相似,但接种高滴度疫苗的女婴死亡率稍高,女婴死亡率与男婴的死亡率之比为1.2。随着疫苗滴度的升高,男婴的死亡率下降,但女婴中死亡率升高与高滴度疫苗相关。对照组男婴最初的死亡危险性较大。在20月龄前接种三种滴度疫苗的女婴的死亡率相似,但20月龄后高滴度疫苗组的死亡危险性一直保持较高水平。
In August 1987 and November 1988, the authors divided 2097 6-to-11-month-old normal infants attending community outpatient clinics into four groups, who were vaccinated with four different vaccines of the vaccine type Vaccine, moderate and high titers of Schwarz, medium Titers and high titers of Edmonston-Zagreb vaccine, of which 53.8%, 49.8%, 49.1% and 47.2% of the boys inoculated with the above vaccine respectively; 393 infants of 9 months old were vaccinated with Schwarz standard titers (10-3.0 ) ~ 10 ~ (3.7) plaque forming units / dose) as control, of which 50.7% were male infants. The first four vaccines have titers ten times (standard) or 100 (standard) titers higher than the standard. The results showed that infants vaccinated with high-titer Edmonston-Za-greb strains had the highest infant mortality rates. Infants born to moderately titrated Schwarz vaccines had the lowest infant mortality rates; there was no difference in infant mortality rates between vaccinated with different titer or vaccine strains and similar to those vaccinated with standard titer vaccines, but those vaccinated with high-titer vaccines The higher the death rate, the ratio of infant mortality to that of male infants was 1.2. Male infant mortality rates have declined as vaccine titers have risen, but increased infant mortality has been associated with high titered vaccines. The control group had a higher risk of first-time death from the baby boy. Mortality rates for girls vaccinated with three titers before 20 months of age were similar, but the risk of death in the high titer vaccine group remained high after 20 months of age.