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目的探讨中青年胃癌的临床和病理特点。方法收集了1995年1月至1999年12月五年间经临床病理诊断的中青年胃癌89例,并对其临床表现、病理诊断、手术治疗、预后状况等方面进行分析。结果早期胃癌仅16例、占23.5%。组织病理学类型高分化腺癌29.4%,印戒细胞癌22%,低分化癌26.5%,粘液癌16%。恶性程度高的低分化肿瘤占64.4%。结论中青年胃癌发病女性多于男性。临床晚期病例多,病理组织学分化差,早期诊断率低,预后差。故提高对中青年胃癌的认识,做到早期诊断、早期治疗是提高治愈率和延长生存期的关键。
Objective To investigate the clinical and pathological characteristics of young and middle-aged gastric cancer. Methods Eighty-nine cases of young and middle-aged gastric cancer diagnosed by clinical pathology from January 1995 to December 1999 were collected, and their clinical manifestations, pathological diagnosis, surgical treatment and prognosis were analyzed. Results Only 16 cases of early gastric cancer, accounting for 23.5%. Histopathological types of well-differentiated adenocarcinoma 29.4%, signet ring cell carcinoma 22%, poorly differentiated carcinoma 26.5%, mucinous carcinoma 16%. Malignant degree of poorly differentiated tumors accounted for 64.4%. Conclusion The incidence of gastric cancer in young women than in men. More advanced clinical cases, poorly differentiated histopathology, early diagnosis and low prognosis. Therefore, raising awareness of young and middle-aged gastric cancer, so early diagnosis and early treatment is to improve the cure rate and prolong survival of the key.