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应用加速度仪四个成串刺激观察小儿维库溴铵（ＶＣＲ）预注法（ＰＰ）的肌松效应。４０例（ＡＳＡ１～Ⅱ）患者随机分成４组。小儿两组：Ⅰ组ＶＣＲＰＰ剂量４０％ＥＤ９５０．０２ｍｇ·ｋｇ（－１），插管（ＩＴ）剂量０．１ｍｇ·ｋｇ（－１）；Ⅱ组ＶＣＲ用非预注法（ＮＯ－ＰＰ）、ＩＴ剂量０．１２ｍｇ·ｋｇ（－１）。成人两组（对照）：Ⅲ组同Ⅰ组；醇Ⅳ组同Ⅱ组。结果：第Ⅰ、Ⅲ组（ＰＰ）肌松起效时间、高峰时间比第Ⅱ、Ⅳ组（ＮＯ－ＰＰ）明显缩短（Ｐ＜０．０５～０．０１）；小儿的无反应时间、高峰持续时间、２５％恢复期时间比成人组短。本研究为小儿选用非去极化类肌松药来加快气管插管提供了依据。
Four series of accelerators were used to observe the muscle relaxant effects of pediatric vecuronium preconditioning (PP). Forty patients (ASA1 ~ Ⅱ) were randomly divided into four groups. In both groups, the VCRPP dose was 40% ED950.02 mg · kg -1 and the IT dose was 0.1 mg · kg -1 in group Ⅰ. The VCR in group Ⅱ was treated with NO-PP, IT dose 0.12mg · kg (-1). Adult two groups (control): Ⅲ group with Ⅰ group; alcohol Ⅳ group with Ⅱ group. Results: The onset time and the peak time of muscle relaxant in group Ⅰ and group Ⅲ were significantly shorter than those in group Ⅱ and Ⅳ (P <0.05 ~ 0.01). The reaction time and peak Duration, 25% recovery time shorter than adults. This study provides a basis for pediatric non-depolarizing muscle relaxants to speed up tracheal intubation.