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目的分析孝感市2008-2012年疑似预防接种异常反应(AEFI)的发生特征,评价AEFI监测系统运行情况、疫苗接种安全性。方法通过AEFI信息管理系统收集孝感市2008-2012年疑似预防接种异常反应个案数据,采用描述性方法进行流行病学分析。结果全市2008-2012年报告AEFI个案804例,AEFI发生率10.71/10万,其中一般反应652例,占81.09%,异常反应134例,占16.67%,偶合反应10例,占1.24%,待定8例,占1.00%,无疫苗质量事故、差错事故及心因性反应报告。≤2岁年龄组435例,占报告数的54.10%,涉及疫苗31种。结论监测数据表明,全市AEFI监测系统运转正常,所使用的疫苗安全性和预防接种服务质量良好,AEFI主要发生在首剂接种早期小年龄组儿童。
Objective To analyze the occurrence characteristics of suspected AEFI in Xiaoshan City from 2008 to 2012 and evaluate the operation of AEFI monitoring system and the safety of vaccination. Methods AEFI information management system was used to collect data on suspected cases of vaccination in Xiaogan from 2008 to 2012, and the descriptive method was used for epidemiological analysis. Results There were 804 AEFI cases and 10.71 / 100,000 AEFI cases reported in the city from 2008 to 2012. There were 652 cases (81.09%) in general reaction, 134 cases (16.67%) abnormal reaction, 10 cases of coupling reaction (1.24%) and 8 Cases, accounting for 1.00%, no vaccine quality accident, accident and accidental response to the report. 435 cases of ≤2 years old age group, accounting for 54.10% of the reported cases and 31 vaccines. Conclusions Monitoring data indicate that the city’s AEFI monitoring system is functioning properly with good vaccine safety and vaccination services, with AEFI occurring primarily in children of early-age vaccination groups.