单次剂量米索前列醇阴道内放置行计划分娩

• 作 者: 邱晓燕 申玉红 董玉英 江明礼
• 机 构: 上海市第一人民医院妇产科
• 出 处: 上海医科大学学报
• 发表日期: 1998年05期
• 关键词: 米索前列醇 计划分娩 单次剂量 自然分娩率 剖宫产 未产妇 阴道 阴道分娩 宫颈成熟 正常妊娠

目的观察单次剂量米索前列醇用于足月妊娠计划分娩的效果，评价其对母儿的安全性。方法选择１０３例正常妊娠３７～４２周单胎头位未产妇，其宫颈Ｂｉｓｈｏｐ评分≥６分，阴道内放置米索前列醇５０μｇ进行计划分娩。结果日间分娩率在５ｐｍ之前达６４１％，８ｐｍ前达８４５％；自然分娩率６８０％，低位钳产率１６５％，剖宫产率１５５％；阴道分娩平均产程为（５１０±２０３）ｈ，急产发生率为１０７％；子宫过强收缩为２９１％。结论阴道内放置米索前列醇进行计划分娩是一种简便易行、安全有效的方法。

Objective To observe the effect of single-dose misoprostol on planned delivery of full-term pregnancy and to evaluate the safety of it. Methods A total of 103 unmarried women with single fetal head during 37-42 weeks of gestation were enrolled in this study. The cervical Bishop score was ≥6 and the misoprostol was given intravaginally to 50 μg for planned delivery. Results The daytime delivery rate was 641% before 5pm and 845% before 8pm. The natural delivery rate was 680%, the low-yield rate was 165% and the rate of cesarean section was 155%. The vaginal delivery The average labor was (5  10 ± 2  03) h, the incidence of acute birth was 107%; uterine contractions was 291%. Conclusion Intra-vaginal misoprostol for planned delivery is a simple, safe and effective method.