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目的观察无创正压通气(NPPV)治疗矽肺合并呼吸衰竭的疗效及不良反应。方法回顾分析2008年10月至2009年10月在本院住院的20例矽肺合并呼吸衰竭患者,在常规治疗基础上应用BiPAP呼吸机NPPV治疗24h后,观察其心率(HR)、呼吸频率(R)及动脉血气变化。结果治疗24h后患者HR、R均下降(P<0.01),动脉血气明显改善(P<0.01),无严重不良反应发生。结论早期应用NPPV对矽肺合并呼吸衰竭疗效显著。
Objective To observe the efficacy and adverse reactions of noninvasive positive pressure ventilation (NPPV) in the treatment of silicosis complicated with respiratory failure. Methods Twenty patients with silicosis and respiratory failure who were hospitalized in our hospital from October 2008 to October 2009 were retrospectively analyzed. After treatment with BiPAP ventilator NPPV for 24 hours, the heart rate (HR), respiratory rate (R ) And arterial blood gas changes. Results After treatment for 24 h, HR and R decreased (P <0.01), arterial blood gas improved significantly (P <0.01), and no serious adverse reactions occurred. Conclusion Early application of NPPV has a significant effect on silicosis and respiratory failure.