论文部分内容阅读
目的分析新生儿持续肺动脉高压联用西地那非、高频振荡通气的效果。方法采用随机数表法,对我院2015年4月~2016年11月间接收的84例持续肺动脉高压患儿进行分组:研究与对照两组各42例。两组都予以高频振动通气等常规治疗,研究组同时加用西地那非。观察两组用药后血气指标的变化情况,比较临床疗效。结果研究组疗效的总有效率为95.24%,对照组为80.95%。研究组明显高于对照组。两组对比,差异具有统计学意义(P<0.05)。研究组用药后的相关血气指标均明显优于对照组。两组对比,差异具有统计学意义(P<0.05)。结论将西地那非+高频振荡通气疗法积极用于新生儿持续肺动脉高压中,有助于改善患儿的相关血气指标,促进病情恢复。
Objective To analyze the effect of continuous pulmonary hypertension combined with sildenafil and high-frequency oscillatory ventilation in neonates. Methods 84 patients with persistent pulmonary hypertension received in our hospital from April 2015 to November 2016 were divided into two groups according to the random number table method: 42 cases in both study and control groups. Both groups were treated by high-frequency vibration ventilation and other conventional treatment, while the study group plus sildenafil. The change of blood gas index after two groups were observed and the clinical curative effect was compared. Results The total effective rate of the study group was 95.24%, while the control group was 80.95%. The study group was significantly higher than the control group. The difference between the two groups was statistically significant (P <0.05). The relevant blood gas indexes in the study group were significantly better than those in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion The use of sildenafil high-frequency oscillatory ventilation therapy in neonates with persistent pulmonary hypertension will be helpful to improve the related blood gas indexes in children and promote the recovery of the disease.