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采用配对分层随机法按体重将18 只Beagle 犬分为3 组,大剂量组剂量为强骨胶囊0-8g/kg ,小剂量组为0-08g/kg( 大、小两个剂量分别相当于每天临床用药剂量的80 倍和8 倍) 。空白对照组给同体积蒸馏水,每周给药6 次,连续24 周,结果对犬的一般状态、体重、血常规检查、血生化指标及病理学检查均未见有明确的病理影响
Eighteen Beagle dogs were divided into three groups according to body weight by paired stratified randomization method. The dose of high-dose group was 0-8g/kg for Qianggu capsule and 0-08g/kg for low-dose group. 80 times and 8 times the daily dose of the drug.) The control group was given the same volume of distilled water and administered 6 times per week for 24 consecutive weeks. The results showed that there was no clear pathological influence on the dog’s general state, body weight, routine blood tests, blood biochemical indicators, and pathological examination.