宁波市社区中老年人糖尿病前期人群筛查与血脂特征分析

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目的了解社区中老年人中PDM人群的血糖与血脂特征,探讨多指标联合筛查的可行性。方法 9 946名社区中老年人用FPG、2 h PG筛查PDM;选择其中1 048名PDM筛查血脂(TG、CHO、HDL、LDL)、糖化血红蛋白和胰岛素水平,分析其特征。结果 9 946名中老年人,不同性别间FPG、2 h PG水平差异无统计学意义(χ~2=1.53,P=0.217),随年龄增长有增高趋势,差异有统计学意义(χ~2=138.217,P<0.01)。2 h PG检测DM漏检率为13.13%(91/693);PDM漏检率为13.95%(277/1 986)。TG、CHO、HBA1C、HDL、INS、LDL各项都存在超标人群,以CHO最高。结论社区中老年人有大量的PDM和DM隐匿其中,多无临床症状,检出率高于全国平均水平;血脂、糖化血红蛋白与血糖一样,在PDM人群中常伴随发生,联合检测能早期发现PDM及并发症,对监控社区中老年人中DM主要危险因素与血糖稳定有着重要意义,具有推广与应用价值。 Objective To understand the characteristics of blood glucose and blood lipid in PDM population in the community and to explore the feasibility of combined multi-index screening. Methods 9 946 middle-aged and elderly people were screened for PDM by FPG and 2 h PG; 1 048 PDM were screened for the levels of serum lipids (TG, CHO, HDL, LDL), HbA1c and insulin, and their characteristics were analyzed. Results There were no significant differences in the levels of FPG and 2 h PG among 9 946 middle-aged and elderly people (χ ~ 2 = 1.53, P = 0.217), with increasing trend with age, the difference was statistically significant (χ ~ 2 = 138.217, P <0.01). The detection rate of PG in 2 h PG was 13.13% (91/693). The PDM missed detection rate was 13.95% (277/1 986). TG, CHO, HBA1C, HDL, INS, LDL there are all over the crowd, with the highest CHO. Conclusion There are a large number of PDM and DM hidden in the community. There are no clinical symptoms and the detection rate is higher than the national average. Serum lipids and HbA1c are often accompanied with blood glucose in PDM population. Combined detection can detect PDM and Complications, the monitoring of the elderly in community DM major risk factors and blood glucose stability is of great significance, with the promotion and application value.
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