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第一颈椎(Atlas,在人体结构上,第一颈椎让神经通过的出口非常小,和脑干的距离很近)解剖位置略有异常,就可导致局部缺血,最终导致血压水平增加。矫正Atlas到正常的解剖位置,可以使受压的动脉血管得到疏通。因此,本试验研究旨在检验这样一个假设,即,矫正Atlas可以降低高血压患者的血压并能保持这种效果。该试验采用了双盲、安慰剂对照的研究设计,初始共涉及50名服用药物的1期高血压(收缩压140～159mmHg或舒张压90～99mmHg)受试者,被随机分配到治疗组和对照组,治疗组根据NUCCA(National Upper Cervical Chiropractic Association)治疗程序给予Atlas矫正治疗,除此之外没有给予其他任何治疗高血压的方法。为期8周。该研究的主要终点是,比较收缩压和舒张压在基线时和8周后的变化。结果显示,相比对照组,8周后治疗组有90%的血压降低8/5mmHg。该研究受试者的平均年龄为52.7±9.6岁,男性占70%。8周后,治疗组收缩压降低17±9mmHg,对照组降低3±11mmHg(P<0.0001);治疗组舒张压降低10±11mmHg,对照组降低2±7mmHg(P=0.002);治疗组8周后的Atlas横向位移为0.04(基线时为1.0),对照组8周后为0.5(基线时0.6);两组的心率变化没有显著差异性,治疗组平均下降0.3次/分钟,对照组为0.5次/分钟。没有观察到受试者出现任何不良结局。我们认为,Atlas矫正,可以显著降低高血压患者的血压并且能够继续保持;这种效用可以和2种降压药联合治疗的效果相媲美。
The first cervical vertebra (Atlas, in the human body structure, the exit of the first cervical vertebra through the nerve is very small, and the distance between the brain stem) slightly abnormal anatomical location, can lead to ischemia, eventually leading to increased blood pressure levels. Correcting the Atlas to a normal anatomical location allows the compressed arteries to be dredged. Therefore, this pilot study aims to test the hypothesis that correcting Atlas can reduce and maintain blood pressure in hypertensive patients. This trial, a double-blind, placebo-controlled study design, initially involved 50 first-phase hypertensive patients with systolic BP 140-159 mmHg or diastolic BP 90-99 mmHg and was randomized to treatment and In the control group, the treatment group was given Atlas orthodontic treatment according to the NUCCA (National Upper Cervical Chiropractic Association) procedure, and no other treatment for hypertension was given. For 8 weeks. The primary endpoint of the study was to compare systolic and diastolic blood pressure changes at baseline and after 8 weeks. The results showed that 90% of the treated group had a blood pressure reduction of 8/5 mmHg after 8 weeks compared to the control group. The average age of the study participants was 52.7 ± 9.6 years and 70% of men. After 8 weeks, the systolic blood pressure was reduced by 17 ± 9 mmHg in the treatment group and by 3 ± 11 mmHg in the control group (P <0.0001). The diastolic blood pressure was reduced by 10 ± 11 mmHg in the treatment group and by 2 ± 7 mmHg in the control group (P = 0.002) After Atlas transverse displacement of 0.04 (baseline 1.0), control group 8 weeks after the 0.5 (baseline 0.6); no significant difference between the two groups of heart rate, the treatment group decreased 0.3 on average / min, the control group was 0.5 Times / minute. No adverse events were observed in the subjects. We believe that Atlas correction can significantly reduce blood pressure in hypertensive patients and can continue to maintain; this effect can be and two kinds of antihypertensive drugs combined treatment effect is comparable.